Category Archives: Asbestos

Scientist looking at DNA

New Data Suggest Over-representation of Young Females in 108 Talc-Exposed Mesothelioma Cases Reported by Drs. Moline and Kradin – A Data Compilation

For talc/asbestos litigation, a notable development in 2020 was the publication of two case series articles involving a total of 108 persons who developed mesothelioma.  The authors concluded that all 108 persons could be characterized as having exposure to asbestos only through cosmetic talcum powder. The authors include Dr.  Jacqueline Moline and Dr. Richard Kradin, […]

Genomic Evidence Essential to Asbestos and Talc Cases: Dr. Len van Zyl Presents at Perrin National Conference

On September 9, Dr. Len van Zyl of ToxicoGenomica presented at Perrin Conferences’ National Asbestos Litigation Conference at the Fairmont San Francisco Hotel. The conference was greatly attended, and attendees were provided with key information on the trends that are currently driving asbestos litigation and the impact these trends may have on future cases. Dr. […]

Perrin conference

The Application of Genomics in Asbestos and Talc Cases: Dr. Len van Zyl will be Speaking at the Perrin National Asbestos Litigation Conference

On September 9-11, Dr. Len van Zyl of ToxicoGenomica will be speaking at Perrin Conferences’ National Asbestos Litigation Conference at the  Fairmont San Francisco Hotel, San Francisco, CA. This marks the tenth anniversary of the three-day conference which provides attendees with a deeper understanding of the trends currently driving asbestos litigation and the impact these […]

mid atlantic conference

The Science & Medicine of Genetic Testing in Asbestos and Talc Cases

As we have written over the past few years, expert testimony involving genetic findings is becoming more and more common in asbestos litigation. As we wrote previously, on Wednesday, July 17 (2019) Dr. Len van Zyl of ToxicoGenomica presented at the Perrin Mid-Atlantic Asbestos Conference where he discussed important new emerging science relevant to the […]

conference

The Time for Genomic Analyses in Asbestos Cases is Now

Expert testimony involving genetic findings is more and more common in asbestos litigation. Recent studies published in the peer-reviewed scientific literature have evaluated a variety of genetic factors (e.g., inherited genetic mutations, micro-RNA, gene expression profiles, and epigenetic factors) in people with and without asbestos exposure. Investigators have found evidence to support the fact that […]

DNA

Why Do BAP1 Mutations Cause Mesothelioma?

Mechanistic understanding of cancers continues to accelerate, with important implications for tort litigation. A recent new study by He et al. (2019) provides new insights into how and why germline BAP1 mutations are involved in the development of some cancers, such as mesothelioma, but not others. The new insights are about tissue specific actions of […]

Expert Planning Meeting for National Mesothelioma Patient Registry – March 26, 2019 in Bethesda

At long last, plans are moving forward to establish a national mesothelioma patient registry in the United States. A key meeting of experts planning the registry will be held on Tuesday March 26, 2019  in Bethesda. The meeting will include panel presentations by mesothelioma experts from CDC and NIOSH, and will include a substantial opportunity for […]

journal of clinical oncology

New Evidence of Genetic Drivers for Mesothelioma In Persons With No Known Asbestos Exposure

A recently published article authored by Drs. Michele Carbone, Haining Yang, and Harvey Pass (among others) is relevant to asbestos and talc defendants because it provides additional data supporting the conclusion that inherited genetic variations cause mesothelioma in some persons without any known exposure to asbestos. Most notably for asbestos and talc litigants, 57 out […]

DNA

New Developments in Genetic Knowledge for Defendants in Asbestos Cases (On Demand Webinar)

The use of genomic evidence in cancer cases is now commonplace, including both talc and traditional asbestos cases. However, the list of relevant genes goes far beyond BAP1 or any other single gene mutation. On Tuesday, October 30, 2018, ToxicoGenomica offered a complimentary webinar educating defense attorneys on the use of genomics in toxic tort […]

Genetic testing concept, DNA icon, medical doctor, isolated on white

Courtroom Implications of New Paper On Germline (Inherited) Mutations Associated with Mesotheliomas (and Perhaps Ovarian Cancers)

This is our second comment on a very recent paper (Panou 2018) reporting findings from a study looking for germline (inherited) variants (mutations) in persons afflicted by mesotheliomas. The paper reported results from a custom gene panel analysis of 195 genes associated with cancers to study a cohort of 198 persons, mainly persons who were […]