ToxicoGenomica Blog

DNA

Perrin Conferences Presents: 2023 Brings Multiple Waves of Additional Studies Regarding Mesotheliomas and Other Cancers Caused Solely by Genomic Factors

| June 1, 2023

Join us for this complimentary CLE webinar on Tuesday, July 18, 2023 from 2:00-3:30 pm ET. This webinar will focus on the latest publications, scientific studies, and statistics regarding genomics role in cancers. It will also cover predictive software and other tools for understanding the impact of germline mutations on disease development and progression. There […]

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DNA

Perrin Conferences Presents: Cutting-Edge Issues in Asbestos Litigation

| March 2, 2023

Kirk Hartley of ToxicoGenomica will cover the topic of the continually increasing value of genomic analysis to evaluate mesothelioma causation at the upcoming Perrin Conference on Cutting-Edge Issues in Asbestos Litigation. As part of a panel on genetics and science, Kirk will discuss important new papers with data showing the increasing findings of genomic drivers of mesotheliomas. One portion […]

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Key Developments in the Use of Genomics in Mesothelioma Cases: Causal Role of BAP1 Null (Loss of Function) Mutations in Mesothelioma and Key Legal Findings

| December 19, 2022

ToxicoGenomica recently presented a webinar organized by Perrin Conferences and the slides are now available for download. The title of the session was Key Developments: Genomics in Mesothelioma Cases. The webinar focused on the latest cases, the most recent science and publications, and the evolving applications and cost of deployment of the science of genomics […]

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Perrin Conferences Present: Key Developments – Genomics in Mesothelioma

| November 21, 2022

Complimentary CLE Webinar Thursday, December 1st, 2022 1:30-2:45 ET Click Here For More Information and to Register This webinar will focus on the latest cases, the most recent science and publications, and the evolving applications and cost of deployment of the science of genomics to understanding the causes of cancer. MEET THE SPEAKERS • Kirk […]

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How hidden protective mutations can change the course of a toxic tort case

| June 8, 2022

Identifying protective mutations through comprehensive genetic screening gives litigators more leverage to argue disease causation in court. Protective mutations are certain altered points in an individual’s DNA that can give them robust resistance to developing disease even if exposed to a known causative agent. Accordingly, if genetic testing shows that a particular person harbors resistance […]

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Findings from new ALS genetics study could change courtroom arguments

| May 25, 2022

Stakeholders involved in toxic tort litigation involving Amyotrophic Lateral Sclerosis (ALS) will want to understand the implications of a recent study that identified previously unknown genetic factors involved in the development of this disease. The authors explained that the results are notable for multiple reasons, including “reveal[ing] genetic variants that protect against ALS by reducing […]

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Newly discovered features of glioblastoma could change the course of legal defenses

| May 11, 2022

Legal defenses in toxic tort cases regarding mesothelioma or lymphoma are increasingly dependent on genetic evidence demonstrating genetic predisposition – i.e., demonstrating that the cancer was caused by genetic defects that the plaintiff inherited. In the case of other cancers, however, litigators may face a lack of data supporting legal arguments of predisposition. For litigators […]

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New clarity on cancer causation with the very first, gap-free sequence of the human genome

| April 27, 2022

Two decades after the initial draft from the Human Genome Project, the very first seamless and gap-free sequence of the entire human genome has been completed by the Telomere to Telomere (T2T) consortium. Researchers involved in the breakthrough call this advancement “[critical] for understanding the genetic contributions to certain diseases”. In toxic tort, this advancement […]

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Federal MDL Judge Issues Lone Pine Order Requiring Precise Form of Genetic Testing for 1,700 Mass Tort Claims

| April 13, 2022

The well-known life sciences legal expert Jim Beck published a blog post this week covering a recent toxic tort case that included a very precise use of genetic evidence. In the publication, Mr. Beck describes a recent instance of a federal MDL judge issuing a Lone Pine order that compels plaintiffs to provide genomic data […]

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ToxicoGenomica at Perrin Conference 2022: Cancer Causation in Toxic Tort Cases

| March 22, 2022

The recent Perrin Conference on Cutting-Edge Issues in Asbestos Litigation (March 7 and 8, 2022) included a panel on the very cutting edge topic of using genetic sequencing data in litigation involving mesotheliomas and other cancers. Our Kirk Hartley presented and covered a wide range of topics at some of the many intersections between science […]

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